LANDSCAPE OF DILI-RELATED ADVERSE DRUG REACTION IN CHINA MAINLAND

Landscape of DILI-related adverse drug reaction in China Mainland

Drug-induced liver injury (DILI) is a type of bizarre adverse drug reaction (ADR) damaging liver (L-ADR) which may lead to substantial hospitalizations and mortality.Due to the general low incidence, detection of L-ADR remains an unsolved public health challenge.Therefore, we used the data of 6.673 million of ADR reports from January 1st, 2012 to D

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Exploiting the yeast L-A viral capsid for the in vivo assembly of chimeric VLPs as platform in vaccine development and foreign protein expression.

A novel expression system based on engineered variants of the yeast (Saccharomyces cerevisiae) dsRNA virus L-A was developed allowing the in vivo assembly of chimeric virus-like particles (VLPs) as a unique platform for a wide range of applications.We show that polypeptides fused to the viral capsid protein Gag self-assemble into isometric Moisturi

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A 2-D guinea pig lung proteome map

Guinea pigs represent an important model for a number of infectious and non-infectious pulmonary diseases.The guinea pig genome has recently been sequenced to full coverage, opening up new research avenues using genomics, transcriptomics and proteomics techniques in Gift this species.In order to further annotate the guinea pig genome and to facilit

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Data Collection Framework for Energy Efficient Privacy Preservation in Wireless Sensor Networks Having Many-to-Many Structures

Wireless sensor networks (WSNs) generally have a many-to-one structure so that event information flows from sensors to a unique sink.In recent WSN applications, many-to-many structures evolved due to the need for conveying collected event information to multiple sinks.Privacy preserved data collection models in the literature do not solve the probl

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